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Preclinical toxicological data: Acute and subacute toxicity studies in rats did not reveal any mortality or significant organ toxicity, even at doses well above therapeutic doses (up to 100 times the effective dose)

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Its aqueous and methanolic extract yield promising results against HepG2 liver cancer cells in a concentration-dependent manner

In fact, their high levels can cause an excessive supply of energy substrates to the metabolic pathways of adipose and non-adipose cells, which leads to a high production of ROS [64]