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Transcriptional analysis of forelimb buds from E12.5 mice showed that expression of genes in the entire cholesterol biosynthesis pathway was upregulated in the limbs of conditional knockout (CKO) mice, and that cholesterol deficiency explained most of the phenotype

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Peptide-encoding mRNA barcodes for the high-throughput in vivo screening of libraries of lipid nanoparticles for mRNA delivery