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Hypertens Res 28(3):215221 Almeida L, Nunes T, Costa R, Rocha JF, Vaz-da-Silva M, Soares-da-Silva P (2013) Etamicastat, a novel dopamine -hydroxylase inhibitor: tolerability, pharmacokinetics, and pharmacodynamics in patients with hypertension

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Excessive ROS can damage DNA, lipid peroxidation, and cause various issues including cancer (Bickers and Athar 2006