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33ppm (see Table 2).Table 2: CO concentration(ppm) in the exhaled air before and after smoking quitting For 14 smokers after having used the smoking-quitting article, the average value of the sulfocyanate concentration in the spit fluid drops from the original 26g/ml to 20g/ml while for 57 smokers after having used the smoking quitting article, their smoking quantity drops in different degrees and the average value of sulfocynate concentration in the spit fluid drops from the original 54

A study showed that HTP (mainly IQOS) use led to abnormal DNA methylation and gene expression profiles, yet to a lower extent than CS 109

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