GLP-1 and GIP receptor agonists have a low intrinsic risk of causing hypoglycaemia when used alone, because their insulin-stimulating effects are glucose-dependent
This was exemplifi ed by the fact that urinary excretion of methylcobalamin was one-third less that of cyanocobalamin.[1] Another point of interest regarding B12 supplementation is the commonly held belief that intramuscular injections of B12 are more effective than oral supplementation
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Neurological symptoms such as paraesthesia, ataxia, and cognitive impairment can occur before haematological changes and may become irreversible if treatment is delayed
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