The two values are comparable both from low-receptor-density cAMP assays (Coskun 2022 explicitly used Willard 2020's method), with a small cross-lab offset (~1.2, gauged from native-ligand controls) so treat the ~16 as a ratio rather than an exact multiple
Potential Combination Approaches: Given the distinct mechanisms of different peptides, combination protocols may offer advantages
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doi: 10.1227/01.NEU.0000170438.13677.22