In a multicenter population-based study, a prevalence of 2.45% was obtained in a Spanish adult sample, similar to the rate for the whole of Europe which was 2.64%
and Herzenberg, L.A., 2007
Testing may be considered for: Confirming kidney function when creatinine-based eGFR is borderline or questionable Earlier detection of reduced kidney filtration Monitoring kidney status in patients using multiple medications or supplements Evaluating kidney reserve before more intensive detoxification, metabolic, or supplement protocols Assessing cardiorenal and metabolic risk more accurately Clarifying kidney function when creatinine appears normal but clinical concern remains Functional Medicine Relevance Cystatin C can be a valuable addition to a functional medicine assessment because kidney filtration affects detoxification capacity, mineral handling, blood pressure regulation, metabolic health, cardiovascular risk, medication clearance, and tolerance of higher-dose nutritional protocols
The duration of cycles and breaks depends on the specific study design
For a higher dose, take 12 sprays by mouth twice daily