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Patients with a history of trauma do best (Koebner)

Patients with gut conditions, including coeliac, Crohn's and significant IBS, are the third group

However, the biological effectsincreased synaptic density, elevated expression of synaptogenic proteins like synaptophysin and PSD-95, and enhanced dendritic spine formationpersist for 7-14 days after administration

This decline appears causally related to decreased regenerative capacity, as exogenous administration restores youthful tissue repair patterns

Green tea supplementation in ISO-administered rats prevented inflammatory cell infiltration, cardiomyocyte hypertrophy, and fibrosis (Fig