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The reference substances were 4-(N-nitrosomethylamino)-1-(3-pyridyl)-1-butanone (NNK), N-nitrosonornicotine (NNN), N-nitrosoa-natabine (NAT) and N-nitrosoanabasine (NAB) (Sigma Aldrich, USA) to analyze the content of TSNAs

And while some suggest that they may not be as harmful as cigarettes and vaping because they dont contain tobacco, there are other concerns, including nicotines effects on cardiovascular and oral health (more on that below)

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[38] Although the plastic is broken down, it is still a man-made material that does not biodegrade

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