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3c), which aligns with the fact that AIM does not dissociate from IgM during SDSpolyacrylamide gel electrophoresis in non-reducing conditions 22

At best, about half of all patients become unresponsive to their current therapy and need to be switched up to another, more toxic drug

This process was repeated three times to obtain Fractions 24

B-complex vitamins serve as coenzymes or precursors in numerous biochemical reactions, and together they work synergistically to support metabolism, neurological function, and cellular energy production

Therefore, elucidating the mechanistic involvement of ferroptosis and current research limitations is essential for guiding the development of targeted therapeutic and preventive strategies