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Beyond passive diffusion and transcellular transport, these transporters can be broken down into five additional categories: active efflux transport, carrier-mediated transport, receptor-mediated transport, absorptive-mediated transport, and ion transporters (Fig

In another word, the regulation of APAP detoxification at the phase II level is beneficial in alleviating APAP hepatotoxicity

A selective depletion of mitochondrial GSH by chronic ethanol exposure has been consistently reported 32

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These logistical factors affect planning but not the actual dosing process