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Further research is necessary to support its use
As with CYP2E1, there are substantial inter-ethnic differences in CYP2D6 across populations, ranging from complete loss of function or reduction in functional activity (2570% of the population, dependent on ethnic origin and geographical location) to extensive, ultra-rapid metabolisers (1.59.3% of the population) (see Table 3 in the supplementary data for a summary of the evidence) [17, 38]
Nonsegmental vitiligo is the most common type of vitiligo where depigmented patches appear on both sides of the body
Improved Nutrient Absorption: A healthy gut environment facilitated by prebiotics improves the absorption of nutrients essential for skin health, such as vitamins and minerals
However, the convergence of outcomes between the treatment groups after 5 years was significant, and a large loss of patients to follow-up is suspected to have biased the treatment effect calculations
