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These two drugs have been found to display competitive blocking effect in short-term kinetic, whereas long-term reaction analysis revealed their irreversible inhibitory effect by forming a stable complex of enzyme-bound intermediates [91]

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Weeks 16 through 24 and beyond: maintenance phase If the combination has been well-tolerated through the titration phase, maintenance involves continuing both compounds at their established doses while reducing bloodwork frequency to monthly

The term organic component as used hereinafter refers to mixtures comprising said phospholipid, lipophilic additives and organic solvents