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Some authors posit that long-term Selank use may cause desensitization of the GABAergic system, resulting in increased anxiety, depression, insomnia, and related issues

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doi: 10.1097/00075198-200102000-00001 21 MoraesTJDowneyGP

Insulin gene transcription and translation, as well as the enhancement of glucose-stimulated insulin secretion (insulinotropic effects), are caused by GLP- 1 receptor activation in the beta cell

But remember, the absence of visible changes does not guarantee potency