The idea is that injecting glutathione gives higher, more immediate systemic levels than oral or topical forms, which theoretically could affect skin pigmentation more strongly
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By reducing the electric potential at the inner mitochondrial membrane below 200 mV (negative inside), it inhibits ATP synthase (complex V) and increases the accumulation of several-fold drugs inside the mitochondria, leading to alterations in processes in the mitochondria matrix [270]
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