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Int Immunopharmacol 116:109740 Zaman R, Islam RA, Ibnat N, Othman I, Zaini A, Lee CY, Chowdhury EH (2019) Current strategies in extending half-lives of therapeutic proteins

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By tethering itself to a large circulating protein, cagrilintide is shielded from renal filtration and enzymatic degradation, extending its half-life to roughly 159195 hours about a week against pramlintides 2045 minutes