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These effects are typically mild to moderate, dose-dependent, and tend to diminish with continued use and proper dose escalation

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Vernoux T, Wilson RC, Seeley KA

Medical Monitoring Patients receive structured follow-ups and supervised dosing to ensure safety and maximize benefit

Treatment B consisted of 385 mg BSE which contained 115 mol (50 mg) GR and 100 mg vitamin C (as ascorbic acid), and was reliant on gut bacteria to perform the conversion, which typically results in higher SF in colon and systemic locations, but overall lower total conversion 63,64