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Notably, breast cancer cells achieve metabolic adaptation by hijacking the autophagy mechanism: under glucose-deprivation conditions, MANF-mediated mitophagy eliminates dysfunctional mitochondria through the PRKN/Parkin-dependent pathway, maintains the ATP supply and promotes tumour survival [112], suggesting that targeting the MANFPRKN interaction can break the drug resistance barrier of breast cancer under metabolic stress
(2004) 2003:Cd004497
On the basis of this evidence, antioxidants represent a logical therapeutic strategy for the treatment of chronic liver disease and the effective advancement in the antiviral treatments against chronic hepatitis C is necessary
To ensure adequate absorption of phosphatidylcholine (PC), you can incorporate certain dietary sources rich in PC into your daily meals
Moreover, IHC analysis in tumors revealed a strong positive correlation between FADS and PCBP2 expression ( R = 0.598, P 1, P 1.5 or 2 or 15% mitochondria genes were excluded
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