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This review systematically introduces the antioxidant mechanism of NAC, analyzes the advancements in NAC-related research involving mesenchymal stem cells, precursor cells, innate immune cells and animal models, discusses its function using the classic oral microenvironment as an example, and places particular emphasis on the innovative applications of NAC-modified tissue engineering biomaterials

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In the case of metastatic breast cancer, combining ipilimumab and nivolumab with anthracycline-based chemotherapy leads to an escalation in toxic side effects without yielding any clinical benefits