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NE contributes to production of hyperconcentrated airway mucus and airway obstruction (59, 123, 124)

Patients with stage 2 hypertension (moderate or severe) are at a relatively higher risk for cardiovascular events (such as strokes, heart attacks, and heart failure), kidney failure and vision problems, so prompt treatment is clinically relevant

PMID 6066618

Weak, anemic animals eat less, grow slower, and are more susceptible to disease

The rapid activation and resolution of immune and inflammatory responses, accompanied by the secretion of numerous proteins, lipids, and other mediators, incur a significant bioenergetic cost requiring the increased uptake of glucose, fatty acids, and amino acids