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In Achilles transection and ligament injury models, it counteracts corticosteroid impairment, elevates collagen deposition, and increases biomechanical strength

As a cofactor for the mitochondrial enzymes including pyruvate dehydrogenase and alphaketoglutarate dehydrogenase, lipoic acid can exert antioxidant effects by directly eliminating ROS, chelating with metal ions, and enhancing endogenous antioxidant capacity [186, 187]

Possession for research purposes may be permitted under specific conditions, but injecting unapproved peptides carries legal and health risks

For severe sagging, surgery is still the best option

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