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Pen Dosage Chart Dosage & Protocols Variations Standard Research Protocol Dose: 0.1 0.3 mg (= 412 clicks) Duration: 2 4 weeks Frequency: Once daily, prior to rest phase Cycle Interval: 2 weeks off before repeating Goal / Description: Baseline protocol used in sleep architecture and circadian rhythm research models

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doi: 10.1097/SHK.0000000000002404 140