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Description

Panels A, B, and C show the percentage of surviving hepatocytes for a 15 g dose, for an 18 g dose, and for a 30 g dose for males and females, respectively

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The activity of NRF2 is highly dependent on several signaling pathways, including protein kinase RNAlike endoplasmic reticulum kinase (PERK) pathway and mitogenactivated protein kinase (MAPK) pathway, making it a complex and contextdependent transcription factor [79, 80]

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GSTs are phase 2 enzymes, ubiquitously distributed in the cell

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