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In laboratory testing, it did not inhibit related SAM-dependent methyltransferases or interfere with other enzymes in NAD+ salvage pathways

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[14] The authors themselves framed this as a first report in a psychiatric population whose generalizability awaits further study. It is a correlation in a small, non-representative sample supportive of DSIP-LI being associated with slow-wave sleep, silent on whether injecting DSIP causes it

These may include issues related to intestinal permeability, irritation, or imbalance within the gut environment