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Goals of Treatment Eliminating the entire at risk mucosa Minimizing complications Minimizing recurrence, strictures and bleeding Decreasing the need for frequent surveillance To meet these objectives, the correct depth ablation should target to, but not beyond, the muscularis mucosa

Glycolate and 2-phosphoglycolate content of tissues measured by ion chromatography coupled to mass spectrometry

Arterioscler Thromb Vasc Biol 37:23112321 Hayashi K, Saga H, Chimori Y, Kimura K, Yamanaka Y, Sobue K (1998) Differentiated phenotype of smooth muscle cells depends on signaling pathways through insulin-like growth factors and phosphatidylinositol 3-kinase

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Osellame LD, Duchen MR (2013) Defective quality control mechanisms and accumulation of damaged mitochondria link Gaucher and Parkinson diseases