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concerning research gaps, it identifies critical areas requiring further exploration, such as developing dose-response models for the nutrient-microbiota inhibition axis and investigating potential synergistic effects among nutrients

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Moreover, direct NAD + supplementation in naturally aging mice restores oocyte numbers and developmental potential, leading to significant improvement in pregnancy outcomes [361]

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Individuals at risk of deficiency, such as vegetarians, vegans, older adults, or those with digestive disorders, may benefit from Vitamin B12 injections