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The resulting particles were subjected to non-uniform 3D refinement, followed by a final local Euler angle local refinement to generate the final consensus maps from which the -helical domain (AHD) of the G s protein and the detergent micelle were masked out

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Zepbound ( tirzepatide ) is a dual glucose-dependent insulinotropic polypeptide (GIP) receptor and glucagon-like peptide-1 receptor agonist (GLP-1)

doi:10.1210/jc

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