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The expression has been connected with a couple of men with the family name Onions, but the usage predates both of them

Scientists Discover Why Quitting Smoking Can Cause Temporary Depression Canadian scientists say that very heavy smokers who quit smoking can experience a spike in an enzyme called MAO-A

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Activation of cholinergic, dopaminergic and serotonergic neurons stimulates the release of cardioactive substances that increase heart rate in Drosophila (Malloy et al., 2017)