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It is a major cellular antioxidant, involved in defense against oxidative stress and redox signaling

doi: 10.1038/228620a0 28 QianB-ZPollardJW

This cell danger response is an evolutionary adaptation enabled to protect the cells and host from harm (414416)

If, like most Canadians and Americans, you are getting enough vitamins from your diet, taking more will not sharpen your focus

HIF-1 orchestrates this adaptation under low oxygen tension, transcriptionally activating glycolysis-associated genes such as glucose transporters (GLUT1/3), glycolytic enzymes (HK1/2, ENO1, PGK1, PKM2), and lactate dehydrogenase A (LDHA), thereby shifting energy production from oxidative phosphorylation to aerobic glycolysis (9496)