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rosea root extracts used in clinical trials

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Its a naturally occurring copper peptide, and researchers have studied it extensively because of its role in boosting collagen production, tissue remodeling, wound healing, skin firmness, skin elasticity, and cellular regeneration

10.3390/biom12071004 Biomolecules 241 PolymeropoulosM

[16] Although cyanocobalamin lacks a defined upper-toxicity threshold due to its water solubility and renal elimination, exceptionally high cumulative doses have been temporally associated with acneiform eruptions, altered potassium homeostasis, and theoretical thrombotic risk, emphasizing the importance of evidence-based dosing