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Recently, our group showed that orally dosed GGC (2 and 4 g) is bioavailable and can increase intracellular GSH levels above homeostasis in lymphocytes of healthy, non-fasting human subjects with no adverse effects (Zarka and Bridge, In conclusion, this study has shown that GGC can decrease apoptosis, oxidative stress and inflammation in human astrocytes and protect astrocytes from oligomeric A 40 -mediated cytotoxicity cellular GSH depletion