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Studies have shown that astragalus can enhance antioxidant capacity in fish and also has a positive alleviating effect on blood biochemistry (42)

Besides that, GPx3 knock-down results in a decreased proliferation, synthesis of DNA and increased apoptosis in spermatogonial stem cells in men [24]

The effects of an estrogen and glycolic acid cream on the facial skin of postmenopausal women: a randomized histologic study

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In addition, albumin nanoparticles can bypass the hENT1-dependent uptake pathway due to their natural targeting (binding to the tumor microenvironment through SPARC protein) and unique transmembrane mechanisms (such as gp60 receptor mediated transport), directly increasing the concentration of gemcitabine in resistant tumor cells, and have shown advantages in overcoming hENT1-deficient resistance in pancreatic cancer and bladder cancer models (Bartkowski et al., 2024