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In this answer 3 sections The reason you started with intense every other day B12 shots and transitioned to a monthly schedule is a medical strategy called loading and maintenance. When you were first diagnosed, your bodys B12 stores were dangerously low

More significant structural improvements reduced fine lines, improved firmness, better skin density typically become visible between weeks 8 and 12, with continued improvement through months 4 to 6 as collagen remodeling matures

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Neither approach shows a meaningful difference in outcomes

Storage: You can keep it in a dry and cool place and make it avoid sunlight