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Most clients are able to return to normal activities immediately following treatment

doi:10.1016/j.freeradbiomed.2012.05.025, PMID: 22634394 Townsend DM, Manevich Y, He L, Hutchens S, Pazoles CJ, Tew KD (2009) Novel role for glutathione S -transferase piRegulator of protein S-glutathionylation following oxidative and nitrosative stress

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This effect is usually mild and not consistent, but it can matter if you are sensitive to stress hormones