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Upon exposure to n-3 PUFAs, Th17 cells generated reduced quantities of proinflammatory cytokines like IL-17, IL-22, and IL-23, whereas Treg cells demonstrated elevated production of anti-inflammatory molecules such as Foxp3 ( DHA has been shown to mitigate the conversion of cells into the Th1/Th17 lineage ( 3.1.1.2 n-6 PUFA The n-6 family of PUFAs comprises key members like linoleic acid (LA) and arachidonic acid (AA), which are notably pro-inflammatory in nature

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The impact these receptors have with respect to their activation by cannabinoids on individual cell-types will be discussed in more detail below (Figure 2B)

Genes with WT1 targeting promoters include IGF-1R and IGF-2