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Liver Function Tests elevation and HBeAg Cirrhosis Cirrhosis Cirrhosis is a late stage of hepatic parenchymal necrosis and scarring (fibrosis) most commonly due to hepatitis C infection and alcoholic liver disease

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As previously mentioned, at high concentrations, NO tends to combine with superoxide to form peroxynitrite ( Negative effectsinhibit mitochondrial respiration and/or induce cell death Although the exact mechanisms are undetermined, peroxynitrite is known to irreversibly inhibit mitochondrial respiration