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Hepatotoxicity with high-dose green tea extract: effect of catechol-O-methyltransferase and uridine 5'-diphospho-glucuronosyltransferase 1A4 genotypes

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Thus, the mutant Asn240Lys demonstrates that the amino acid at the 1 st activity controller position can influence the tyrosinase activity but is not able to completely shut down monophenolase activity