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Although PPIs exhibit exceptional acid inhibition effects, various studies have linked PPI use with adverse digestive events, such as small intestinal bacterial overgrowth (SIBO) and Clostridium difficile infection

Apr 2018;36(2):115-122

Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human NPS

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This highlights the need for strategies to overcome the restrictive nature of the BBB and the lack of drug targeting specificity which hinder delivery of adequate drug concentrations in the affected brain regions