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Saoli M

We also failed to detect an increase in MitoSOX-sensitive mitochondrial ROS production in erastin-treated RPE cells

Pharmacophore modeling is a powerful tool for drug discovery, but its effectiveness heavily relies on the availability of both active molecules and the biological target ( 3.6 Experimental validation After applying the virtual screening protocol (Supplementary Figures S2), we identified 18 candidate molecules based on their docking scores and MMGBSA free energy calculations

Although ML162 shares similar structural and biological characteristics with RSL3, it exhibits greater activity

BLA was conducted based on lung imaging findings of inflammation or atelectasis