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However, metformin, an AMPK activator, can reverse this defect, presenting a novel therapeutic approach for drug-resistant pneumonia (55)

Autoantibodies against HSP70 family proteins were detected in the cerebrospinal fluid from patients with multiple sclerosis

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PTP1B is particularly notable: it dephosphorylates InsRec and IRS proteins, is expressed in liver, skeletal muscle, and adipose tissue, and remains a candidate therapeutic target in obesity, metabolic syndrome, and T2DM [227,228,229]