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Detection method: Colorimetric method

Dysbiosis, characterized by a reduction in beneficial SCFAs and an increase in uremic toxins (IS, PCS, TMAO, and IAA), damages the intestinal barrier and elevates LPS and pro-inflammatory cytokines (TNF-, IL)

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Ethacrynic acid and quinine, which are both GST inhibitors, have been reported to reverse the resistance to melphalan and doxorubicin of cancer cell lines with increased GST expression [25]

mBio 15 (10): e0207524