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On day 10, half of the tumor bearing mice were locally irradiated with a single dose of 15 Gy, of which 4 animals received sertraline treatment and 4 received DMSO

Enhanced with the substitution of an Arginine for the third position of its amino acid sequence and an extension peptide at the N-terminus, IGF-1 LR3 is designed to boost the biological activity of the IGF hormone

These peptides have a very long half-life (around 7 days), so the timing is not critical, but consistency is

J Gene Med