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Although Drp1-Ser637 phosphorylation predominantly suppresses mitochondrial fission under most physiological conditions, emerging evidence indicates its biological functions exhibit cell type-specific dependency and are dynamically regulated by microenvironmental signaling cues and upstream regulatory networks (Serasinghe and Chipuk, 2017)

The results of the Phase I clinical trial were promising, demonstrating good tolerability in both healthy subjects and patients with rheumatoid arthritis (RA)

PCBP1 protects bladder cancer cells from mitochondria injury and ferroptosis by inducing LACTB mRNA degradation