Compound 105 was then converted to compound 106 in analogous fashion to compound 103 in Example 88, except that 2-methoxypyrimidin-5-ylboronic acid was used in the place of l-methyl-6-oxo-l,6- dihydropyridin-3-ylboronic acid, pinacol ester to provide compound 106
Randomization was conducted by an independent researcher who was not involved in patient enrollment, treatment administration, or outcome evaluation, ensuring allocation concealment
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In phosphorylated form, it is a coenzyme in the metabolism of amino acids (decarboxylation, transamination, etc.)
In addition, impaired vitamin D signaling pathways have been indicated in thyroid cancer