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Principle coordinates analyses (PCoAs) were generated based on the distance and dissimilarity matrices

NICE notes that pernicious anaemia is the most common cause of Vitamin B12 deficiency in those aged 40-70, with an average onset age of 60 in white people and 50 in black people, although it can affect black women at a younger age

Altering this pathway through NNMT inhibition has been shown in preclinical settings to increase caloric expenditure while reducing storage

Preclinical studies indicate that NNMT knockdown or inhibition can protect against diet-induced weight gain and improve metabolic parameters without reducing food intake