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Nonspecific binding was blocked by immersing the slides in 2% BSA in PBS for 90 min and incubating with background sniper (Biocare, #BS966) for 10 min

This leads to increased production and transfer of melanosomes to keratinocytes, with inflammatory mediators like leukotrienes and prostaglandins further exacerbating the condition 129

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(warfarin)) always reduced bleeding time and/or haemorrhage and counteracted thrombocytopenia

Additionally, ONOO-induced post-translational modifications impair the activities of both GCL and GSH synthetase, further reducing GSH synthesis [122]