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Glutathione S -transferase enzymes catalyze its conjugation to lipophilic xenobiotics, facilitating their excretion or further metabolism

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Eid HM, Elkomy MH, El Menshawe SF, & Salem HF

Abnormal methyl cycle and dependent methylations can be caused by genetic alteration, toxic chemicals, or dietary deficiencies 3 , and contribute to the etiology of many pathologies including cancer 4,5 , diabetes 6 , atherosclerosis and cardiovascular diseases 7,8,9 , birth defects 10 , and neurodegenerative diseases 11