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In brief, HEK293T cells (American Type Culture Collection (ATCC), CRL-3216) were cultured in complete DMEM (Gibco, 11965-092) supplemented with 10% (v/v) FBS (VWR, 97068-085) and 1% penicillinstreptomycin (VWR, 16777-164) at 37 C under 5% CO 2

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Hyperpigmentation This solid soap bar helps to fade discoloration, blemishes, and uneven skin tone, revealing a more radiant and even complexion over time

145,146,286 Cells lacking arginine-succinate synthetase 1 (ASS1) are arginine-dependent