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However, the absence of FDA approval for any medical indication, limited large-scale trials, and variability in product formulations underscore the need for caution [10, 11]

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[5] It proceeds via acid-base catalysis through a three-step mechanism, involving two strictly conserved amino acid residues, a lysine (Lys) and a glutamate (Glu)

[44] in colorectal cancer cells, where ER-bound regions are highly enriched for the AP-1 motif

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