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Tobacco business in Korea was strictly managed by the government from the late 1940s under the Monopoly Bureau of the Economy Ministry

Another study assessing vascular pathomechanisms indicated a 10 to 20-fold lower effect of IQOS compared to CS on the adhesion of monocytic cells on human coronary arterial endothelial cells (a surrogate of atherogenesis) 66

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When inhaled, they land on special receptors in the nasal lining, or mucosa